2-Methoxy-11-hydroxyaporphine


SMILES CN1CCC2=C3C1CC4=C(C3=CC(=C2)OC)C(=CC=C4)O
InChIKey UGNGRDRWDHJJJI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 281.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 7.34 7.34 7.34 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 PDSP Ki database
D1 DRD1 Human Dopamine A pKi 7.34 7.34 7.34 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.63 6.63 6.63 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database