{3-[2-Chloro-thioxanthenylidene]-propyl}-methyl-[4-(3-piperidin-1-yl-propoxy)-benzyl]-amine


SMILES CN(CCC=C1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl)CC4=CC=C(C=C4)OCCCN5CCCCC5
InChIKey DSRXHDAICZGTCK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 532.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 6.53 6.53 6.53 PDSP Ki database
H3 HRH3 Human Histamine A pKi 8.81 8.81 8.81 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.28 7.28 7.28 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 7.3 7.3 7.3 PDSP Ki database
D5 DRD5 Human Dopamine A pKi 6.53 6.53 6.53 PDSP Ki database
D1 DRD1 Human Dopamine A pKi 6.61 6.61 6.61 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database