(-)-trans-3-Cyclopropylmethyl-9-methoxy-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinoline


SMILES COC1=CC=CC2=C1OC3C24CCN(CC4CCC3)CC5CC5
InChIKey GGRHHMUDPLWGFI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 313.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 5.0 6.2 7.39 PDSP Ki database
δ OPRD Human Opioid A pKi 5.0 5.63 6.26 PDSP Ki database
μ OPRM Human Opioid A pKi 5.0 6.26 7.52 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database