cefapirin
SMILES | CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CSC1=CC=NC=C1)C2=O)C(O)=O |
InChIKey | UQLLWWBDSUHNEB-CZUORRHYSA-N |
Chemical properties
Hydrogen bond acceptors | 8 |
Hydrogen bond donors | 2 |
Rotatable bonds | 7 |
Molecular weight (Da) | 423.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pIC50 | 8.26 | 8.26 | 8.26 | Drug Central |
5-HT2B | 5HT2B | Human | 5-Hydroxytryptamine | A | pIC50 | 8.32 | 8.32 | 8.32 | Drug Central |
α2C | ADA2C | Human | Adrenoceptors | A | pIC50 | 8.33 | 8.33 | 8.33 | Drug Central |
D2 | DRD2 | Human | Dopamine | A | pIC50 | 8.33 | 8.33 | 8.33 | Drug Central |
D3 | DRD3 | Human | Dopamine | A | pIC50 | 8.34 | 8.34 | 8.34 | Drug Central |
D4 | DRD4 | Human | Dopamine | A | pIC50 | 8.3 | 8.3 | 8.3 | Drug Central |
H2 | HRH2 | Human | Histamine | A | pIC50 | 8.28 | 8.28 | 8.28 | Drug Central |
δ | OPRD | Human | Opioid | A | pIC50 | 8.3 | 8.3 | 8.3 | Drug Central |
κ | OPRK | Human | Opioid | A | pIC50 | 8.28 | 8.28 | 8.28 | Drug Central |
μ | OPRM | Human | Opioid | A | pIC50 | 8.27 | 8.27 | 8.27 | Drug Central |
SST4 | SSR4 | Human | Somatostatin | A | pIC50 | 8.29 | 8.29 | 8.29 | Drug Central |
NK2 | NK2R | Human | Tachykinin | A | pIC50 | 8.31 | 8.31 | 8.31 | Drug Central |
CB1 | CNR1 | Human | Cannabinoid | A | pIC50 | 8.39 | 8.39 | 8.39 | Drug Central |
NK1 | NK1R | Human | Tachykinin | A | pIC50 | 8.31 | 8.31 | 8.31 | Drug Central |