Ligand Data
Ligand
Name | LY2119620 |
SMILES | CN1CCN(CC1)C(=O)COc1nc2sc(c(c2c(c1Cl)C)N)C(=O)NC1CC1 |
InChIKey | TYTGOXSAAQWLPJ-UHFFFAOYSA-N |
Type | small-molecule |
External Links | |
Structure pdb | 4MQT 6OIK 6U1N |
Structure
Properties
Hydrogen bond acceptors | 7 |
Hydrogen bond donors | 2 |
Rotatable bonds | 5 |
Molecular weight | 437.1 |
Bioactivity
Receptor | Affinity (nM) | Potency (nM) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Min | Avg | Max | Min | Avg | Max |
M2 | ACM2 | Human | Acetylcholine (muscarinic) | A (Rhodopsin) | 3548 | 6401 | 9333 |