labetalol



labetalol


SMILES CC(CCc1ccccc1)NCC(O)c1ccc(O)c(C(=N)O)c1
InChIKey SGUAFYQXFOLMHL-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors 4
Hydrogen bond donors 5
Rotatable bonds 8
Molecular weight (Da) 328.2

Database connections

Ligand site mutations β1 5-HT1A

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

labetalol


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 9
Phase II 27
Phase III 9
Phase IV 21

Database connections

Ligand site mutations β1 5-HT1A

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score