loxiglumide


SMILES CCCCCN(C(=O)C(NC(=O)c1ccc(c(c1)Cl)Cl)CCC(=O)O)CCCOC
InChIKey QNQZBKQEIFTHFZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 14
Molecular weight (Da) 460.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Rat Cholecystokinin A pKi 5.0 6.02 6.57 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK1 CCKAR Rat Cholecystokinin A pIC50 6.5 6.5 6.5 Guide to Pharmacology
CCK1 CCKAR Human Cholecystokinin A pIC50 6.71 6.71 6.71 ChEMBL
CCK1 CCKAR Rat Cholecystokinin A pIC50 8.19 8.19 8.19 Drug Central
CCK1 CCKAR Human Cholecystokinin A pIC50 8.17 8.17 8.17 Drug Central