LPA
| SMILES | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O |
| InChIKey | WRGQSWVCFNIUNZ-KTKRTIGZSA-N |
Chemical properties
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 3 |
| Rotatable bonds | 20 |
| Molecular weight (Da) | 436.3 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Endogenous |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| LPA3 | LPAR3 | Human | Lysophospholipid (LPA) | A | pKd | 6.69 | 6.69 | 6.69 | Guide to Pharmacology |
| LPA4 | LPAR4 | Human | Lysophospholipid (LPA) | A | pKd | 7.35 | 7.35 | 7.35 | Guide to Pharmacology |
| LPA5 | LPAR5 | Human | Lysophospholipid (LPA) | A | pKd | 8.19 | 8.19 | 8.19 | Guide to Pharmacology |
| LPA4 | LPAR4 | Mouse | Lysophospholipid (LPA) | A | pKd | 7.35 | 7.35 | 7.35 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| LPA2 | LPAR2 | Human | Lysophospholipid (LPA) | A | pEC50 | 6.71 | 7.44 | 8.16 | Guide to Pharmacology |
| LPA5 | LPAR5 | Human | Lysophospholipid (LPA) | A | pEC50 | 4.3 | 6.1 | 7.9 | Guide to Pharmacology |
| LPA6 | LPAR6 | Human | Lysophospholipid (LPA) | A | pEC50 | 6.0 | 6.0 | 6.0 | Guide to Pharmacology |
| GPR87 | GPR87 | Human | A orphans | A | pEC50 | 7.44 | 7.44 | 7.44 | Guide to Pharmacology |
| P2RY10 | P2Y10 | Human | A orphans | A | pEC50 | 6.9 | 6.9 | 6.9 | Guide to Pharmacology |
| LPA1 | LPAR1 | Mouse | Lysophospholipid (LPA) | A | pEC50 | 7.9 | 8.1 | 8.3 | Guide to Pharmacology |
| LPA2 | LPAR2 | Mouse | Lysophospholipid (LPA) | A | pEC50 | 8.0 | 8.09 | 8.17 | Guide to Pharmacology |
| LPA3 | LPAR3 | Mouse | Lysophospholipid (LPA) | A | pEC50 | 6.6 | 6.6 | 6.6 | Guide to Pharmacology |
| LPA4 | LPAR4 | Human | Lysophospholipid (LPA) | A | pEC50 | 6.24 | 6.24 | 6.24 | ChEMBL |
| LPA2 | LPAR2 | Human | Lysophospholipid (LPA) | A | pEC50 | 8.52 | 8.52 | 8.52 | ChEMBL |
| LPA1 | LPAR1 | Human | Lysophospholipid (LPA) | A | pEC50 | 7.1 | 7.1 | 7.1 | ChEMBL |
| LPA3 | LPAR3 | Human | Lysophospholipid (LPA) | A | pEC50 | 6.54 | 6.54 | 6.54 | ChEMBL |
| LPA5 | LPAR5 | Human | Lysophospholipid (LPA) | A | pEC50 | 6.85 | 6.85 | 6.85 | ChEMBL |
| LPA6 | LPAR6 | Mouse | Lysophospholipid (LPA) | A | pEC50 | 6.0 | 6.0 | 6.0 | Guide to Pharmacology |