CHEMBL1242352


SMILES COc1ccccc1N1CCN(CC2OCC(c3ccccc3)(c3ccccc3)O2)CC1
InChIKey XRKSDOUDYWUZPR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 430.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 8.17 8.17 8.17 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.09 9.09 9.09 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 9.58 9.58 9.58 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.64 7.73 7.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database