LY2828360


SMILES CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2C4CCOCC4)C5=CC=CC=C5Cl
InChIKey UCMNDPDJRSEZPL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 7.39 7.39 7.39 Guide to Pharmacology
CB2 CNR2 Rat Cannabinoid A pKi 7.44 7.44 7.44 Guide to Pharmacology
CB2 CNR2 Rat Cannabinoid A pKi 7.4 7.42 7.43 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 7.39 7.41 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pEC50 7.7 7.7 7.7 Guide to Pharmacology
CB2 CNR2 Human Cannabinoid A pEC50 7.16 7.51 7.7 ChEMBL