CHEMBL1259071


SMILES Cc1ccc(CNCC2(F)CCN(C(=O)c3cc(Br)cs3)CC2)nc1
InChIKey VSVDMIMYERSROL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 425.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 4.75 4.75 4.75 ChEMBL
D1 DRD1 Pig Dopamine A pKi 4.47 4.47 4.47 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.7 5.7 5.7 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.72 4.72 4.72 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.0 4.07 4.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 7.77 7.77 7.77 ChEMBL