CHEMBL1259216


SMILES CN1CCN(C2Cc3ccccc3Sc3ccc(-c4nnn(C)n4)cc32)CC1
InChIKey VYGJNGJRTPHPPA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 392.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Golden hamster Adrenoceptors A pKi 9.46 9.46 9.46 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pKi 9.77 9.77 9.77 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKi 9.0 9.0 9.0 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKi 9.82 9.82 9.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.64 9.0 9.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database