norfluoxetine


SMILES NCCC(c1ccccc1)Oc1ccc(cc1)C(F)(F)F
InChIKey WIQRCHMSJFFONW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 295.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.3 5.3 5.3 Guide to Pharmacology
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 Guide to Pharmacology
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.54 6.95 7.51 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.53 6.53 6.53 PDSP Ki database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.04 7.04 7.04 PDSP Ki database
H1 HRH1 Human Histamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.0 5.15 5.3 PDSP Ki database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.92 5.92 5.92 PDSP Ki database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.34 5.34 5.34 PDSP Ki database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.12 6.12 6.12 PDSP Ki database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.59 5.59 5.59 PDSP Ki database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.66 5.66 5.66 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database