VUF-5297


SMILES N[C@H]1C[C@@H]1c1c[nH]cn1
InChIKey OWWNABDDYQLERE-WHFBIAKZSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 123.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.6 8.24 8.76 ChEMBL
H3 HRH3 Human Histamine A pKi 8.03 8.03 8.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 5.15 5.15 5.15 ChEMBL
H2 HRH2 Human Histamine A pEC50 6.16 6.16 6.16 ChEMBL
H1 HRH1 Human Histamine A pEC50 6.06 6.06 6.06 ChEMBL
H3 HRH3 Human Histamine A pEC50 7.38 7.8 8.23 ChEMBL