ONO-8711


SMILES OC(=O)CCC/C=C\[C@H]1C2CCC([C@@H]1CNS(=O)(=O)c1ccc(cc1C)Cl)CC2
InChIKey VVEXPDRCGCQELD-CFDZEDGGSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 439.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pKi 9.2 9.2 9.2 Guide to Pharmacology
TP TA2R Human Prostanoid A pKi 7.1 7.1 7.1 Guide to Pharmacology
EP1 PE2R1 Mouse Prostanoid A pKi 8.8 8.8 8.8 Guide to Pharmacology
EP3 PE2R3 Mouse Prostanoid A pKi 7.17 7.17 7.17 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database