(-)-pentazocine


SMILES CC(=CCN1CC[C@@]2([C@H]([C@H]1Cc1c2cc(cc1)O)C)C)C
InChIKey VOKSWYLNZZRQPF-GDIGMMSISA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 285.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.3 7.3 7.3 Guide to Pharmacology
κ OPRK Human Opioid A pKi 7.8 8.2 8.6 Guide to Pharmacology
μ OPRM Human Opioid A pKi 8.4 8.4 8.4 Guide to Pharmacology
κ OPRK Human Opioid A pKi 8.66 8.66 8.66 ChEMBL
μ OPRM Human Opioid A pKi 8.41 8.41 8.41 ChEMBL
δ OPRD Human Opioid A pKi 6.74 7.12 7.31 PDSP Ki database
κ OPRK Human Opioid A pKi 8.52 8.61 8.66 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 8.36 8.36 8.36 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 7.49 7.49 7.49 PDSP Ki database
μ OPRM Human Opioid A pKi 8.16 8.33 8.41 PDSP Ki database
κ OPRK Human Opioid A pKi 8.06 8.06 8.06 Drug Central
μ OPRM Human Opioid A pKi 8.08 8.08 8.08 Drug Central
μ OPRM Rat Opioid A pKi 8.09 8.09 8.09 Drug Central
κ OPRK Guinea pig Opioid A pKi 8.15 8.15 8.15 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 8.14 8.14 8.14 Drug Central