5-(N,N-hexamethylene)-amiloride [301]
5-(N,N-hexamethylene)-amiloride
| SMILES |
NC(N)=NC(=O)c1nc(Cl)c(N2CCCCCC2)nc1N |
| InChIKey |
RQQJJXVETXFINY-UHFFFAOYSA-N |
Chemical Properties
| Hydrogen bond acceptors |
5 |
| Hydrogen bond donors |
3 |
| Rotatable bonds |
2 |
| Log P |
0.506 |
| Molecular weight (Da) |
311.1 |
| Stereochemistry info |
unspecified |
Database connections
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| Ligand site mutations |
A2A
A3
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Bioactivities
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| Receptor |
Activity |
Source |
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Gene |
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Type |
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Avg |
Max |
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| Receptor |
Activity |
Source |
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Gene |
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5-(N,N-hexamethylene)-amiloride
Drug properties
| Molecular type |
Small molecule |
| Physiological/Surrogate |
Surrogate |
| Approved drug |
No |
Distribution across phases (no. indications)
Phase I
0
Phase II
0
Phase III
0
Phase IV
0
Database connections
|
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| Ligand site mutations |
A2A
A3
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Compound is not listed as a drug.