PD 128907


SMILES CCCN1CCO[C@@H]2[C@@H]1COc1c2cc(cc1)O
InChIKey YOILXOMTHPUMRG-JSGCOSHPSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 249.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 5.4 5.9 6.4 Guide to Pharmacology
D3 DRD3 Human Dopamine A pKi 7.6 7.65 7.7 Guide to Pharmacology
D3 DRD3 Human Dopamine A pKd 9.0 9.0 9.0 Guide to Pharmacology
μ OPRM Human Opioid A pKi 4.11 4.11 4.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.12 5.12 5.12 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.25 5.25 5.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database