Pyrazolone, 1


SMILES O=C(Nc1c(C(C)C)n(n(c1=O)c1ccccc1)C)Nc1ccc(cc1)Cl
InChIKey PAEBEUZTAPIOIO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 384.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FPR1 FPR1 Mouse Formylpeptide A pEC50 8.7 8.7 8.7 Guide to Pharmacology
FPR2/ALX FPR2 Human Formylpeptide A pEC50 7.4 7.4 7.4 Guide to Pharmacology
FPR2/ALX FPR2 Mouse Formylpeptide A pEC50 6.92 6.92 6.92 Guide to Pharmacology
FPR1 FPR1 Human Formylpeptide A pEC50 7.29 7.39 7.49 ChEMBL
FPR2/ALX FPR2 Human Formylpeptide A pEC50 7.02 7.28 7.39 ChEMBL