pipotiazine


SMILES OCCC1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)S(=O)(=O)N(C)C
InChIKey JOMHSQGEWSNUKU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 475.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 9.7 9.7 9.7 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 9.7 9.7 9.7 Guide to Pharmacology
D3 DRD3 Human Dopamine A pKi 9.55 9.55 9.55 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database