Ligand Data

Ligand

id 3092
Name ramatroban
SMILES OC(=O)CCn1c2CC[C@H](Cc2c2c1cccc2)NS(=O)(=O)c1ccc(cc1)F
InChIKey LDXDSHIEDAPSSA-OAHLLOKOSA-N
Type small-molecule
External Links
Structure pdb 6IIU

Structure

Properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight 416.1


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
DP1 PD2R Human Prostanoid A (Rhodopsin) 11020 22210 33400
TP TA2R Human Prostanoid A (Rhodopsin) 0.6 7.4 14.0
DP2 PD2R2 Human Prostanoid A (Rhodopsin) 4.3 206.6 754.0