Ligand Data
Ligand
| Name | ramatroban |
| SMILES | OC(=O)CCn1c2CC[C@H](Cc2c2c1cccc2)NS(=O)(=O)c1ccc(cc1)F |
| InChIKey | LDXDSHIEDAPSSA-OAHLLOKOSA-N |
| Type | small-molecule |
| External Links | |
| Structure pdb | 6IIU |
Structure
Properties
| Hydrogen bond acceptors | 4 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 6 |
| Molecular weight | 416.1 |
Bioactivity
| Receptor | Affinity (nM) | Potency (nM) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Min | Avg | Max | Min | Avg | Max |
| DP1 | PD2R | Human | Prostanoid | A (Rhodopsin) | 11020 | 22210 | 33400 | |||
| TP | TA2R | Human | Prostanoid | A (Rhodopsin) | 0.6 | 7.4 | 14.0 | |||
| DP2 | PD2R2 | Human | Prostanoid | A (Rhodopsin) | 4.3 | 206.6 | 754.0 | |||