CHEMBL140278


SMILES Oc1ccc2c3c1O[C@H]1[C@H](O)CC[C@@]4(O)[C@@H](C2)N(CC2CC2)CC[C@]314
InChIKey JLVNEHKORQFVQJ-PYIJOLGTSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 343.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.67 6.97 7.28 ChEMBL
κ OPRK Human Opioid A pKi 8.13 8.73 9.32 ChEMBL
μ OPRM Human Opioid A pKi 8.67 9.2 9.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pIC50 7.7 8.18 8.74 ChEMBL
δ OPRD Human Opioid A pIC50 7.5 7.59 7.64 ChEMBL
μ OPRM Human Opioid A pEC50 8.92 8.92 8.92 ChEMBL