Ligand Data

Ligand

id 32425
Name CHEMBL140299
SMILES COc1cccc(C(CNC(=O)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)N2CCC(N3CCCCC3)CC2)c1
InChIKey LLCSACQWSCTAJV-UHFFFAOYSA-N
Type small-molecule
External Links

Structure

Properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight 571.3


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
NK1 NK1R Human Tachykinin A (Rhodopsin) 1.5 1.5 1.5