apadenoson


SMILES CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(C#CC[C@@H]1CC[C@H](CC1)C(=O)OC)nc2N
InChIKey FLEVIENZILQUKB-XTWQNQIISA-N

Chemical properties

Hydrogen bond acceptors 11
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 486.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A1 AA1R Human Adenosine A pKi 7.11 7.11 7.11 Guide to Pharmacology
A2A AA2AR Human Adenosine A pKi 9.3 9.3 9.3 Guide to Pharmacology
A3 AA3R Human Adenosine A pKi 7.35 7.35 7.35 Guide to Pharmacology
A3 AA3R Human Adenosine A pKi 7.35 7.35 7.35 ChEMBL
A1 AA1R Human Adenosine A pKi 7.11 7.11 7.11 ChEMBL
A2A AA2AR Human Adenosine A pKi 9.3 9.3 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database