Sb 243213

Chemical Properties

SMILES O=C(N1CCc2c1cc(c(c2)C)C(F)(F)F)Nc1ccc(nc1)Oc1cccnc1C
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight 428.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey ZETBBVYSBABLHL-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 Guide to Pharmacology
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 Guide to Pharmacology
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 9.0 9.0 9.0 Guide to Pharmacology
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 6.18 6.18 6.18 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 9.15 9.15 9.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.49 7.49 7.49 ChEMBL