CHEMBL135878


SMILES COc1ccccc1N1CCN(CCC(=O)c2csc3ccccc23)CC1
InChIKey VFVYVWQENQPQHA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 380.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.3 5.3 5.3 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.3 6.3 6.3 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.36 7.36 7.36 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.36 7.36 7.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database