GPCRdb

rimonabant

Agent/drug
Bioactivity

rimonabant

SMILES	Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1
InChIKey	JZCPYUJPEARBJL-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	4
Molecular weight (Da)	462.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

κ	OPRK	Rat	Opioid	A	pKi	7.24	7.24	7.24	PDSP Ki database
CB₁	CNR1	Human	Cannabinoid	A	pKi	7.90	8.30	8.70	Guide to Pharmacology
CB₁	CNR1	Mouse	Cannabinoid	A	pKi	8.30	8.58	8.82	ChEMBL
CB₁	CNR1	Mouse	Cannabinoid	A	pKd	6.72	6.72	6.72	ChEMBL
CB₁	CNR1	Human	Cannabinoid	A	pKi	6.84	8.26	9.72	ChEMBL
CB₁	CNR1	Human	Cannabinoid	A	pKd	8.59	8.62	8.74	ChEMBL
CB₁	CNR1	Human	Cannabinoid	A	pKi	7.33	8.42	9.72	PDSP Ki database
CB₁	CNR1	Rat	Cannabinoid	A	pKi	8.02	8.02	8.02	Drug Central
CB₁	CNR1	Mouse	Cannabinoid	A	pKi	8.05	8.05	8.05	Drug Central
CB₁	CNR1	Human	Cannabinoid	A	pKi	8.01	8.01	8.01	Drug Central
CB₂	CNR2	Mouse	Cannabinoid	A	pKi	5.79	6.12	6.43	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pKi	5.11	6.17	8.96	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pKi	5.70	6.08	6.90	PDSP Ki database
CB₂	CNR2	Human	Cannabinoid	A	pKi	8.05	8.05	8.05	Drug Central
CB₂	CNR2	Mouse	Cannabinoid	A	pKi	8.19	8.19	8.19	Drug Central

Showing 1 to 15 of 15 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Mouse	Cannabinoid	A	pEC50	5.05	5.05	5.05	ChEMBL
CB₁	CNR1	Mouse	Cannabinoid	A	pIC50	7.60	7.60	7.60	ChEMBL
CB₁	CNR1	Human	Cannabinoid	A	pIC50	6.80	8.08	8.87	ChEMBL
CB₁	CNR1	Human	Cannabinoid	A	pEC50	6.23	7.93	9.96	ChEMBL
CB₂	CNR2	Mouse	Cannabinoid	A	pEC50	7.82	7.82	7.82	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pIC50	5.01	5.87	8.72	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pEC50	4.51	4.51	4.51	ChEMBL
GPR18	GPR18	Human	GPR18, GPR55 and GPR119	A	pIC50	5.00	5.00	5.00	ChEMBL
GPR18	GPR18	Human	GPR18, GPR55 and GPR119	A	pEC50	5.00	5.00	5.00	ChEMBL
GPR18	GPR18	Human	GPR18, GPR55 and GPR119	A	pIC50	8.30	8.30	8.30	Drug Central
GPR55	GPR55	Human	GPR18, GPR55 and GPR119	A	pEC50	5.26	5.90	6.55	Guide to Pharmacology
GPR55	GPR55	Human	GPR18, GPR55 and GPR119	A	pEC50	5.70	5.70	5.70	ChEMBL
GPR55	GPR55	Human	GPR18, GPR55 and GPR119	A	pEC50	8.24	8.24	8.24	Drug Central
M₂	ACM2	Human	Acetylcholine (muscarinic)	A	pIC50	5.21	5.21	5.21	ChEMBL

Showing 1 to 14 of 14 entries

rimonabant

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central GPCRdb

Compound is not listed as a drug.