GPCRdb

saridegib

Agent/drug
Bioactivity

saridegib

SMILES	CC1=C2C[C@H]3[C@@H](CC[C@@H]4C[C@H](NS(C)(=O)=O)CC[C@]34C)[C@@H]2CC[C@@]2(C1)O[C@@H]1C[C@H](C)CN[C@H]1[C@H]2C
InChIKey	HZLFFNCLTRVYJG-WWGOJCOQSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	2
Molecular weight (Da)	504.3

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank PubChem GPCRdb

No bioactivity data available.

saridegib

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 1

Phase II 1

Phase III 4

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

SMO	SMO	Frizzled	Protein receptors	Class F	Basal cell carcinoma of skin, unspecified	2C32.Z		0.570	3	No
SMO	SMO	Frizzled	Protein receptors	Class F	Chondrosarcoma of bone or articular cartilage of unspecified sites	2B50.Z		0.074	2	No
SMO	SMO	Frizzled	Protein receptors	Class F	Gorlin syndrome	LD2D.4		0.310	3	No
SMO	SMO	Frizzled	Protein receptors	Class F	Neoplasms of unknown behaviour of unspecified site	2F9Z		0.520	3	No
SMO	SMO	Frizzled	Protein receptors	Class F	Other specified malignant neoplasms of pancreas	2C10.Y		0.207	1	No

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