sumanirole


SMILES CN[C@@H]1Cc2cccc3c2n(C1)c(=O)[nH]3
InChIKey RKZSNTNMEFVBDT-MRVPVSSYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 203.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 5.2 5.83 6.26 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.79 6.99 8.05 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.14 7.14 7.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.1 8.1 8.1 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 6.17 6.45 6.73 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.26 7.09 8.34 ChEMBL
D2 DRD2 Rat Dopamine A pEC50 7.46 7.71 7.97 ChEMBL