CHEMBL1455766


SMILES Cc1ccc(S(=O)(=O)NCc2ccc(C(=O)NCCN(Cc3ccccc3)C(C)C)cc2)cc1
InChIKey JEJWQCTZDAJWOX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 479.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Rat Opioid A pKi 7.3 7.3 7.3 ChEMBL
δ OPRD Human Opioid A pKi 5.96 5.96 5.96 ChEMBL
μ OPRM Human Opioid A pKi 6.51 6.51 6.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pIC50 5.88 6.19 6.86 ChEMBL
μ OPRM Human Opioid A pIC50 4.85 4.85 4.85 ChEMBL