TM30089


SMILES OC(=O)Cn1c2CCC(Cc2c2c1cccc2)N(S(=O)(=O)c1ccc(cc1)F)C
InChIKey CANCTKXGRVNXFP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 416.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP2 PD2R2 Human Prostanoid A pKi 8.22 8.72 9.22 ChEMBL
DP1 PD2R Human Prostanoid A pKi 6.18 6.18 6.18 ChEMBL
DP2 PD2R2 Human Prostanoid A pKi 9.22 9.22 9.22 Guide to Pharmacology
TP TA2R Human Prostanoid A pKi 5.86 5.86 5.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP2 PD2R2 Human Prostanoid A pIC50 8.44 8.44 8.44 ChEMBL
DP2 PD2R2 Human Prostanoid A pIC50 8.92 8.92 8.92 Guide to Pharmacology