VIP


SMILES None
InChIKey VBUWHHLIZKOSMS-UHFFFAOYSA-N
Sequence HSDAVFTDNYTRLRKQMAVKKYLNSILN

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Endogenous
Approved drug No

Database connections

Ligand site mutations VPAC1 VPAC2

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAC1 PACR Human VIP and PACAP B1 pKi 6.900000000000001 6.9 6.9 Guide to Pharmacology
VPAC1 VIPR1 Human VIP and PACAP B1 pKi 9.2 9.2 9.2 Guide to Pharmacology
VPAC2 VIPR2 Human VIP and PACAP B1 pKi 8.433333333333334 8.43 8.43 Guide to Pharmacology
PAC1 PACR Rat VIP and PACAP B1 pKi 5.65 5.65 5.65 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
VPAC2 VIPR2 Human VIP and PACAP B1 pEC50 9.72 9.72 9.72 ChEMBL
secretin SCTR Human Glucagon B1 pIC50 5.4 5.4 5.4 Guide to Pharmacology
PAC1 PACR Human VIP and PACAP B1 pEC50 7.0 7.0 7.0 Guide to Pharmacology
PAC1 PACR Human VIP and PACAP B1 pIC50 6.0 6.0 6.0 Guide to Pharmacology
VPAC1 VIPR1 Human VIP and PACAP B1 pEC50 9.0 9.0 9.0 Guide to Pharmacology
VPAC1 VIPR1 Human VIP and PACAP B1 pIC50 8.680000000000001 8.68 8.68 Guide to Pharmacology
VPAC2 VIPR2 Human VIP and PACAP B1 pEC50 8.333333333333334 8.33 8.33 Guide to Pharmacology
VPAC2 VIPR2 Human VIP and PACAP B1 pIC50 8.2 8.2 8.2 Guide to Pharmacology
PAC1 PACR Rat VIP and PACAP B1 pEC50 7.1 7.1 7.1 Guide to Pharmacology
PAC1 PACR Rat VIP and PACAP B1 pIC50 5.7 5.7 5.7 Guide to Pharmacology
VPAC1 VIPR1 Rat VIP and PACAP B1 pIC50 8.799999999999999 8.8 8.8 Guide to Pharmacology
VPAC2 VIPR2 Rat VIP and PACAP B1 pIC50 8.266666666666666 8.27 8.27 Guide to Pharmacology
secretin SCTR Rat Glucagon B1 pIC50 6.2 6.2 6.2 Guide to Pharmacology