Chembl101361

Chemical Properties

SMILES COc1cc2c(cc1OC)C1=NO[C@@H](CN3CCN(C/C=C(\C)c4ccccc4OC)CC3)[C@@H]1CO2
Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight 493.3

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey NJTFNKZJGXSOMJ-CACUEOBGSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pKi 9.05 9.05 9.05 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.28 8.28 8.28 ChEMBL