CHEMBL143355
SMILES | N#Cc1ccc2[nH]cc(CN3CCN(c4ccccc4Cl)CC3)c2c1 |
InChIKey | SNFLVHDMWFYRRB-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 1 |
Rotatable bonds | 3 |
Molecular weight (Da) | 350.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D1 | DRD1 | Bovine | Dopamine | A | pKi | 6.29 | 6.29 | 6.29 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 7.77 | 7.77 | 7.77 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 5.85 | 6.06 | 6.27 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.26 | 6.26 | 6.26 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |