Chembl104484

Chemical Properties

SMILES CN1CCC(c2c[nH]c3ccc(NC(=O)c4ccc(C#N)cc4)nc23)CC1
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight 359.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey CDOSRLXPFHPFFJ-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.14 8.14 8.14 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.51 6.51 6.51 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL