Asimadoline


SMILES O[C@H]1CCN(C1)C[C@@H](N(C(=O)C(c1ccccc1)c1ccccc1)C)c1ccccc1
InChIKey JHLHNYVMZCADTC-LOSJGSFVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 414.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 9.0 9.0 9.0 Guide to Pharmacology
κ OPRK Guinea pig Opioid A pKi 8.7 8.7 8.7 ChEMBL
δ OPRD Human Opioid A pEC50 5.1 5.1 5.1 ChEMBL
κ OPRK Human Opioid A pEC50 9.3 9.3 9.3 ChEMBL
μ OPRM Human Opioid A pEC50 4.22 4.22 4.22 ChEMBL