Chembl156639


SMILES CCCN(CCN1CCN(c2ccccc2)CC1)C1CCc2ccc(O)cc2C1
InChIKey POVCSYONXDMZKL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 393.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.81 8.81 8.81 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.85 6.85 6.85 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.76 8.79 8.81 ChEMBL
D3 DRD3 Human Dopamine A pEC50 9.16 9.16 9.16 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.67 6.76 6.85 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.91 7.91 7.91 ChEMBL