CHEMBL105803


SMILES c1ccc(COC[C@H]2CC[C@H](c3c[nH]cn3)O2)cc1
InChIKey RETVAMKTDRMQFH-UKRRQHHQSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 258.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 5.98 5.99 6.0 ChEMBL
H3 HRH3 Human Histamine A pKi 6.6 6.61 6.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 6.1 6.12 6.13 ChEMBL
H3 HRH3 Human Histamine A pEC50 7.0 7.02 7.04 ChEMBL