Chembl160357


SMILES O=C1CCc2ccc(OCCCCN3CCN(c4ccccc4)CC3)cc2N1
InChIKey USIMZAIRLDAIQJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 379.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 9.1 9.25 9.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.37 8.37 8.37 ChEMBL