CHEMBL156845


SMILES COc1cccc(C(=O)NCCN2CCN(c3ccc(C)cc3)CC2)c1
InChIKey LTPWRNUOYXUBGY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 353.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.04 8.04 8.04 ChEMBL
D4 DRD4 Human Dopamine A pKi 10.6 10.6 10.6 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.37 6.37 6.37 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.13 5.13 5.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database