β-endorphin
SMILES | None |
InChIKey | JMHFFDIMOUKDCZ-NTXHZHDSSA-N |
Sequence | YGGFMTSEKSQTPLVTLFKNAIIKNAYKKGE |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Endogenous/Surrogate | Endogenous |
Approved drug | No |
Database connections
Structure pdb | 8F7Q |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
δ | OPRD | Human | Opioid | A | pKi | 8.3 | 8.3 | 8.3 | Guide to Pharmacology |
κ | OPRK | Human | Opioid | A | pKi | 6.3 | 7.1 | 7.9 | Guide to Pharmacology |
δ | OPRD | Mouse | Opioid | A | pKi | 9.0 | 9.0 | 9.0 | Guide to Pharmacology |
μ | OPRM | Rat | Opioid | A | pKi | 9.0 | 9.0 | 9.0 | Guide to Pharmacology |
κ | OPRK | Rat | Opioid | A | pKi | 6.8 | 6.8 | 6.8 | Guide to Pharmacology |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
κ | OPRK | Mouse | Opioid | A | pIC50 | 7.4 | 7.4 | 7.4 | Guide to Pharmacology |