β-endorphin


SMILES None
InChIKey JMHFFDIMOUKDCZ-NTXHZHDSSA-N
Sequence YGGFMTSEKSQTPLVTLFKNAIIKNAYKKGE

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Endogenous
Approved drug No

Database connections

Structure pdb 8F7Q

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.3 8.3 8.3 Guide to Pharmacology
κ OPRK Human Opioid A pKi 6.3 7.1 7.9 Guide to Pharmacology
δ OPRD Mouse Opioid A pKi 9.0 9.0 9.0 Guide to Pharmacology
μ OPRM Rat Opioid A pKi 9.0 9.0 9.0 Guide to Pharmacology
κ OPRK Rat Opioid A pKi 6.8 6.8 6.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pIC50 7.4 7.4 7.4 Guide to Pharmacology