CHEMBL160536


SMILES Cc1nn2c(N3CCN(Cc4ccccc4)CC3)cccc2c1CN1CCN(c2ccc(Cl)cc2)CC1
InChIKey OHHKPQVUUXXVGV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 514.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.82 5.82 5.82 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.58 7.58 7.58 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.57 6.57 6.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.52 6.72 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database