oxytocin (Human) [6074]



oxytocin (Human)


SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O
InChIKey XNOPRXBHLZRZKH-DSZYJQQASA-N
Sequence CYIQNCPLG
HELM PEPTIDE1{C.Y.I.Q.N.C.P.L.G.[am]}$PEPTIDE1,PEPTIDE1,6:R3-1:R3$$$

Chemical Properties

Hydrogen bond acceptors 15
Hydrogen bond donors 12
Rotatable bonds 17
Log P -3.609
Molecular weight (Da) 1006.4
Stereochemistry info partial

Database connections

Structure pdb 7RYC 7QVM
Model (Boltz2) OT
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

oxytocin (Human)


Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug Yes

Distribution across phases (no. indications)

Phase I 12
Phase II 22
Phase III 6
Phase IV 3

Database connections

Structure pdb 7RYC 7QVM
Model (Boltz2) OT

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score