CHEMBL1765633


SMILES CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)[C@H]1CCn2nccc2C1
InChIKey UTFOVXIJDJSMKK-VWLOTQADSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 430.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 6.07 8.89 10.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.28 8.64 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 10.25 10.25 10.25 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.43 7.56 9.29 ChEMBL