Chembl1770559
Chemical Properties
| SMILES | O=C(N[C@@H]1CC[C@@H](c2cccc(F)c2F)Cn2cc(CC(F)(F)F)nc21)N1CCC(n2c(=O)[nH]c3ncccc32)CC1 |
| Hydrogen bond acceptors | 6 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 4 |
| Molecular weight | 589.2 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | LEZDWRNJGFRDJB-IIBYNOLFSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| calcitonin-like | CALRL | Human | Calcitonin | B1 | pKi | 8.41 | 8.41 | 8.41 | ChEMBL |
| calcitonin-like | CALRL | Human | Calcitonin | B1 | pIC50 | 7.48 | 7.81 | 8.14 | ChEMBL |