Chembl1770559

Chemical Properties

SMILES O=C(N[C@@H]1CC[C@@H](c2cccc(F)c2F)Cn2cc(CC(F)(F)F)nc21)N1CCC(n2c(=O)[nH]c3ncccc32)CC1
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight 589.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey LEZDWRNJGFRDJB-IIBYNOLFSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
calcitonin-like CALRL Human Calcitonin B1 pKi 8.41 8.41 8.41 ChEMBL
calcitonin-like CALRL Human Calcitonin B1 pIC50 7.48 7.81 8.14 ChEMBL