CHEMBL1771108


SMILES COc1ccccc1N1CCN(CCCCN2CCc3c(cccc3-c3ccccc3)C2=O)CC1
InChIKey VRJXNVWZJIUSSO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 469.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 7.2 7.24 7.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.92 7.92 7.92 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.01 8.01 8.01 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.66 6.66 6.66 ChEMBL
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.64 6.64 6.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database