CHEMBL1771111


SMILES COc1ccccc1N1CCN(CCCCN2CCCc3cc(-c4cccs4)ccc3C2=O)CC1
InChIKey OXVZLPIGSCONSD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 489.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 8.29 8.48 8.68 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.54 9.54 9.54 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.54 8.54 8.54 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.04 6.04 6.04 ChEMBL
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.28 6.28 6.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database