CHEMBL1771112


SMILES COc1ccccc1N1CCN(CCCCN2CCc3cc(-c4ccncc4)ccc3C2=O)CC1
InChIKey PFLVUDAFKXUKEV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 470.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 7.89 8.02 8.15 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.92 9.92 9.92 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.47 8.47 8.47 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.42 6.42 6.42 ChEMBL
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database