CHEMBL1773091


SMILES CO[C@@]12CCCC[C@@]13CCN(CC1CCC1)[C@@H]2Cc1ccc(OC(=O)CCCCCCCCC(=O)OCc2ccccc2)cc13
InChIKey OVPROZAAWKHKOP-GFMHJGOASA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 15
Molecular weight (Da) 615.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 9.64 9.64 9.64 ChEMBL
δ OPRD Human Opioid A pKi 7.85 7.85 7.85 ChEMBL
μ OPRM Human Opioid A pKi 9.82 9.82 9.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 8.68 8.68 8.68 ChEMBL
κ OPRK Human Opioid A pIC50 8.19 8.19 8.19 ChEMBL
μ OPRM Human Opioid A pEC50 8.77 8.77 8.77 ChEMBL
μ OPRM Human Opioid A pIC50 8.12 8.12 8.12 ChEMBL