GPCRdb

β-phenylethylamine

β-phenylethylamine

SMILES	NCCc1ccccc1
InChIKey	BHHGXPLMPWCGHP-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	1
Hydrogen bond donors	1
Rotatable bonds	2
Molecular weight (Da)	121.1

Database connections

Guide To Pharmacology DrugBank ChEMBL_compound_ids PubChem GPCRdb
Ligand site mutations	α_1B

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	4.78	4.78	4.78	ChEMBL
H₁	HRH1	Human	Histamine	A	pKi	3.80	4.40	5.00	PDSP Ki database

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

TA₁	TAAR1	Human	Trace amine	A	pEC50	6.20	6.60	7.00	Guide to Pharmacology
TA₁	TAAR1	Rat	Trace amine	A	pEC50	6.40	6.50	6.60	Guide to Pharmacology
TA₁	TAAR1	Human	Trace amine	A	pEC50	6.89	7.11	7.82	ChEMBL
TA₁	TAAR1	Rat	Trace amine	A	pEC50	6.58	6.81	7.39	ChEMBL
TA₁	TAAR1	Mouse	Trace amine	A	pEC50	6.72	6.99	7.33	ChEMBL
TA₁	TAAR1	Mouse	Trace amine	A	pEC50	6.30	6.85	7.40	Guide to Pharmacology
TAAR4	TAAR4	Mouse	A orphans	A	pEC50	6.00	6.00	6.00	Guide to Pharmacology

Showing 1 to 7 of 7 entries

β-phenylethylamine

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

Guide To Pharmacology DrugBank ChEMBL_compound_ids PubChem GPCRdb
Ligand site mutations	α_1B

Compound is not listed as a drug.

This ligand is endogenous.